Contact Us Live Chat or 1-888-220-8330
Search Bar
Search by Part Number or Keywords
  • My Garage
  • My Account
  • Cart
  • Body & Mirrors
  • Chassis & Brakes
  • Engine & Drivetrain
  • Electrical & Lighting
Help Center
< Back ×
Replacement and OEM Parts for 2021 Lexus IS350 Cooling Systems, Fans, Radiators & Components

2021 Lexus IS350 Cooling Systems, Fans, Radiators & Components

My Vehicle Change Vehicle
2021 Lexus IS350
Change Vehicle
Vehicle Options
We need more information about your vehicle to make a correct determination of fitment

39 products about 2021 Lexus IS350 Cooling Systems, Fans, Radiators & Components found

Show Item:
  • 30
  • 60
  • 90
Sort by:
Recommended
Filter
Sort
View by
  • OEM (Genuine) 2021 Lexus IS350 Filter Element

    PartNumber: 04152-YZZA5
    OEM 2021 Lexus IS350 Filter Element - 04152-YZZA5
    Product Specifications
    • Notes: 2.5 Liter, 3.5 Liter, W/4WD; Is350; AWD
    • Other Names: Element, Oil Filter
    • Item Dimensions: 3.2 x 3.2 x 5.2 inches
    • Item Weight: 0.70 Pounds
    • Replaces: 04152-31030, 04152-31050, 04152-YZZA2, 04152-31060, 04152-38010
    • Part Description: Filter Element
    More Info
    $4.64 MSRP: $5.97
    You Save: $1.33 (23%)
  • OEM (Genuine) 2021 Lexus IS350 Motor, Cooling Fan

    PartNumber: 16363-38160
    OEM 2021 Lexus IS350 Motor, Cooling Fan - 16363-38160
    Product Specifications
    • Other Names: Fan Motor, Motor
    • Item Weight: 7.30 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Motor, Cooling Fan
    More Info
    $206.29 MSRP: $272.77
    You Save: $66.48 (25%)
  • OEM (Genuine) 2021 Lexus IS350 Fan

    PartNumber: 16361-31410
    OEM 2021 Lexus IS350 Fan - 16361-31410
    Product Specifications
    • Notes: 3.5l; Is350; Left
    • Location: Driver Side
    • Other Names: Fan Blade
    • Item Weight: 0.80 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Fan
    More Info
    $65.17 MSRP: $85.50
    You Save: $20.33 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Fan

    PartNumber: 16361-31410
    OEM 2021 Lexus IS350 Fan - 16361-31410
    Product Specifications
    • Notes: 3.5l; Is350; Left
    • Location: Driver Side
    • Other Names: Fan Blade
    • Item Weight: 0.80 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Fan
    More Info
    $65.17 MSRP: $85.50
    You Save: $20.33 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Radiator Assembly

    PartNumber: 16400-31B80
    OEM 2021 Lexus IS350 Radiator Assembly - 16400-31B80
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Radiator
    • Fitment Type: Direct Replacement
    • Part Description: Radiator Assembly
    More Info
    $237.24 MSRP: $313.70
    You Save: $76.46 (25%)
  • OEM (Genuine) 2021 Lexus IS350 Cock, Radiator Drain

    PartNumber: 16417-21280
    OEM 2021 Lexus IS350 Cock, Radiator Drain - 16417-21280
    Product Specifications
    • Notes: W/O 5.0l
    • Item Weight: 0.20 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16417-0C180
    • Part Description: Cock, Radiator Drain
    More Info
    $5.81 MSRP: $7.44
    You Save: $1.63 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Motor, Cooling Fan

    PartNumber: 16363-31300
    OEM 2021 Lexus IS350 Motor, Cooling Fan - 16363-31300
    Product Specifications
    • Notes: 3.5l
    • Location: Driver Side
    • Other Names: Fan Motor, Motor
    • Item Weight: 5.60 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Motor, Cooling Fan
    More Info
    $270.75 MSRP: $366.75
    You Save: $96.00 (27%)
  • OEM (Genuine) 2021 Lexus IS350 Reserve Tank Assembly, R

    PartNumber: 16470-31181
    OEM 2021 Lexus IS350 Reserve Tank Assembly, R - 16470-31181
    Product Specifications
    • Notes: W/O 5.0l
    • Other Names: Reservoir, Reservoir Tank
    • Item Weight: 0.40 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16470-31180
    • Part Description: Reserve Tank Assembly, R
    More Info
    $98.40 MSRP: $129.10
    You Save: $30.70 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Bracket Sub-Assy, Oil Filter

    PartNumber: 15670-31020
    OEM 2021 Lexus IS350 Bracket Sub-Assy, Oil Filter - 15670-31020
    Product Specifications
    • Notes: 2.5 Liter, 3.5 Liter, W/4WD
    • Other Names: Filter Assembly, Housing Assembly, Oil Filter
    • Item Weight: 3.50 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Bracket Sub-Assy, Oil Filter
    More Info
    $258.46 MSRP: $350.11
    You Save: $91.65 (27%)
  • OEM (Genuine) 2021 Lexus IS350 Motor, Cooling Fan

    PartNumber: 16363-31400
    OEM 2021 Lexus IS350 Motor, Cooling Fan - 16363-31400
    Product Specifications
    • Notes: 3.5l
    • Location: Passenger Side
    • Other Names: Fan Motor
    • Item Weight: 2.40 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Motor, Cooling Fan
    More Info
    $248.43 MSRP: $328.49
    You Save: $80.06 (25%)
  • OEM (Genuine) 2021 Lexus IS350 Reserve Tank Assembly, R

    PartNumber: 16470-36032
    OEM 2021 Lexus IS350 Reserve Tank Assembly, R - 16470-36032
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Expansion Tank, Reservoir, Reservoir Tank
    • Fitment Type: Direct Replacement
    • Replaces: 16470-36031
    • Part Description: Reserve Tank Assembly, R
    More Info
    $258.83 MSRP: $350.60
    You Save: $91.77 (27%)
  • OEM (Genuine) 2021 Lexus IS350 Shroud, Fan

    PartNumber: 16711-31610
    OEM 2021 Lexus IS350 Shroud, Fan - 16711-31610
    Product Specifications
    • Notes: 3.5l; Is350
    • Other Names: Fan Shroud, Shroud
    • Item Weight: 2.30 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Shroud, Fan
    More Info
    $143.07 MSRP: $189.18
    You Save: $46.11 (25%)
  • OEM (Genuine) 2021 Lexus IS350 Fan

    PartNumber: 16361-38040
    OEM 2021 Lexus IS350 Fan - 16361-38040
    Product Specifications
    • Notes: 3.5l; Is350; Right
    • Location: Passenger Side
    • Other Names: Fan Blade
    • Item Weight: 0.70 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Fan
    More Info
    $87.19 MSRP: $114.39
    You Save: $27.20 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Fan

    PartNumber: 16361-38040
    OEM 2021 Lexus IS350 Fan - 16361-38040
    Product Specifications
    • Notes: 3.5l; Is350; Right
    • Location: Passenger Side
    • Other Names: Fan Blade
    • Item Weight: 0.70 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Fan
    More Info
    $87.19 MSRP: $114.39
    You Save: $27.20 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Engine Water Pump Assembly

    PartNumber: 16100-09690
    OEM 2021 Lexus IS350 Engine Water Pump Assembly - 16100-09690
    Product Specifications
    • Other Names: Water Pump
    • Item Weight: 3.10 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Engine Water Pump Assembly
    More Info
    $130.68 MSRP: $172.81
    You Save: $42.13 (25%)
  • OEM (Genuine) 2021 Lexus IS350 Computer, Cooling Fan

    PartNumber: 89257-30110
    OEM 2021 Lexus IS350 Computer, Cooling Fan - 89257-30110
    Product Specifications
    • Notes: Is350; Engine Compartment, Cooling Fan, 3.5l
    • Other Names: Control Module
    • Item Weight: 1.00 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Computer, Cooling Fan
    More Info
    $123.78 MSRP: $162.39
    You Save: $38.61 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Water Pump Assembly

    PartNumber: 16100-39616
    OEM 2021 Lexus IS350 Water Pump Assembly - 16100-39616
    Product Specifications
    • Notes: W/O 5.0l, 3.5l
    • Other Names: Water Pump
    • Fitment Type: Direct Replacement
    • Replaces: 16100-39615
    • Part Description: Water Pump Assembly
    More Info
    $126.40 MSRP: $165.82
    You Save: $39.42 (24%)
  • OEM (Genuine) 2021 Lexus IS350 Cap Sub-Assy, Radiator

    PartNumber: 16401-31830
    OEM 2021 Lexus IS350 Cap Sub-Assy, Radiator - 16401-31830
    Product Specifications
    • Notes: W/O 5.0l, 3.5l
    • Other Names: Radiator Cap
    • Item Weight: 0.40 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Cap Sub-Assy, Radiator
    More Info
    $15.05 MSRP: $19.28
    You Save: $4.23 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Sensor, Water Temper

    PartNumber: 89422-47010
    OEM 2021 Lexus IS350 Sensor, Water Temper - 89422-47010
    Product Specifications
    • Notes: Is350
    • Other Names: Coolant Temperature Sensor, Temperature Sensor
    • Item Weight: 0.20 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Sensor, Water Temper
    More Info
    $63.37 MSRP: $81.22
    You Save: $17.85 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Cap, Reserve Tank

    PartNumber: 16475-28140
    OEM 2021 Lexus IS350 Cap, Reserve Tank - 16475-28140
    Product Specifications
    • Notes: Is350
    • Other Names: Cap, Reservoir Cap, Reservoir Tank Cap
    • Item Weight: 0.40 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16475-37010, 16475-51010, 16475-37011, 16475-28120, 16401-53010, 16401-75120
    • Part Description: Cap, Reserve Tank
    More Info
    $23.34 MSRP: $29.93
    You Save: $6.59 (23%)
  • OEM (Genuine) 2021 Lexus IS350 Inlet Sub-Assembly, WATE

    PartNumber: 16031-31071
    OEM 2021 Lexus IS350 Inlet Sub-Assembly, WATE - 16031-31071
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Water Inlet
    • Fitment Type: Direct Replacement
    • Replaces: 16031-31070
    • Part Description: Inlet Sub-Assembly, WATE
    More Info
    $57.34 MSRP: $73.48
    You Save: $16.14 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Outlet Sub-Assy, Water

    PartNumber: 16304-31121
    OEM 2021 Lexus IS350 Outlet Sub-Assy, Water - 16304-31121
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Water Outlet
    • Item Weight: 0.90 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16304-31120
    • Part Description: Outlet Sub-Assy, Water
    More Info
    $52.39 MSRP: $67.15
    You Save: $14.76 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Outlet Sub-Assy, Water

    PartNumber: 16304-31121
    OEM 2021 Lexus IS350 Outlet Sub-Assy, Water - 16304-31121
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Water Outlet
    • Item Weight: 0.90 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16304-31120
    • Part Description: Outlet Sub-Assy, Water
    More Info
    $52.39 MSRP: $67.15
    You Save: $14.76 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Outlet Sub-Assy, Water

    PartNumber: 16304-31121
    OEM 2021 Lexus IS350 Outlet Sub-Assy, Water - 16304-31121
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Water Outlet
    • Item Weight: 0.90 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16304-31120
    • Part Description: Outlet Sub-Assy, Water
    More Info
    $52.39 MSRP: $67.15
    You Save: $14.76 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Hose, Radiator, NO.2

    PartNumber: 16572-31350
    OEM 2021 Lexus IS350 Hose, Radiator, NO.2 - 16572-31350
    Product Specifications
    • Notes: W/O 5.0l, 3.5l
    • Other Names: Lower Hose, Upper Hose
    • Item Weight: 1.00 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Hose, Radiator, NO.2
    More Info
    $39.79 MSRP: $50.99
    You Save: $11.20 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Hose, Radiator, NO.2

    PartNumber: 16572-31350
    OEM 2021 Lexus IS350 Hose, Radiator, NO.2 - 16572-31350
    Product Specifications
    • Notes: W/O 5.0l, 3.5l
    • Other Names: Lower Hose, Upper Hose
    • Item Weight: 1.00 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: Hose, Radiator, NO.2
    More Info
    $39.79 MSRP: $50.99
    You Save: $11.20 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Hose, Radiator, NO.2

    PartNumber: 16572-31570
    OEM 2021 Lexus IS350 Hose, Radiator, NO.2 - 16572-31570
    Product Specifications
    • Notes: W/O 5.0l, 3.5l
    • Other Names: Lower Hose
    • Fitment Type: Direct Replacement
    • Part Description: Hose, Radiator, NO.2
    More Info
    $29.17 MSRP: $37.39
    You Save: $8.22 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Hose, Radiator, NO.2

    PartNumber: 16572-31570
    OEM 2021 Lexus IS350 Hose, Radiator, NO.2 - 16572-31570
    Product Specifications
    • Notes: W/O 5.0l, 3.5l
    • Other Names: Lower Hose
    • Fitment Type: Direct Replacement
    • Part Description: Hose, Radiator, NO.2
    More Info
    $29.17 MSRP: $37.39
    You Save: $8.22 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Gasket, Water Pump

    PartNumber: 16271-0P030
    OEM 2021 Lexus IS350 Gasket, Water Pump - 16271-0P030
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Gasket, Water Pump Gasket
    • Item Weight: 0.60 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16271-31050
    • Part Description: Gasket, Water Pump
    More Info
    $31.64 MSRP: $40.55
    You Save: $8.91 (22%)
  • OEM (Genuine) 2021 Lexus IS350 Gasket, Water Pump

    PartNumber: 16271-0P030
    OEM 2021 Lexus IS350 Gasket, Water Pump - 16271-0P030
    Product Specifications
    • Notes: Is350; W/O 5.0l, 3.5l
    • Other Names: Gasket, Water Pump Gasket
    • Item Weight: 0.60 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16271-31050
    • Part Description: Gasket, Water Pump
    More Info
    $31.64 MSRP: $40.55
    You Save: $8.91 (22%)
1-30 of 39 Results
< Previous
12
Next >