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Replacement and OEM Parts for 2021 Lexus ES350 Cooling Systems, Fans, Radiators & Components

2021 Lexus ES350 Cooling Systems, Fans, Radiators & Components

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2021 Lexus ES350
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57 products about 2021 Lexus ES350 Cooling Systems, Fans, Radiators & Components found

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  • OEM (Genuine) 2021 Lexus ES350 Cock, Radiator Drain

    PartNumber: 16417-21280
    OEM 2021 Lexus ES350 Cock, Radiator Drain - 16417-21280
    Product Specifications
    • Notes: 3.5 Liter, Japan Built;3.5 Liter, US Built
    • Item Weight: 0.20 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16417-0C180
    • Part Description: 2021 Lexus ES350 Cock, Radiator Drain
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $5.72 MSRP: $7.33
    You Save: $1.61 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Clamp, Hose

    PartNumber: 90460-90005
    OEM 2021 Lexus ES350 Clamp, Hose - 90460-90005
    Product Specifications
    • Notes: 3.5 Liter, Japan Built, #1; 3.5 Liter, US Built, #1
    • Other Names: Air Hose Clamp, Clamp, Inlet Tube Clamp
    • Item Weight: 0.40 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Clamp, Hose
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $13.38 MSRP: $17.12
    You Save: $3.74 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Cap Sub-Assy, Radiator

    PartNumber: 16401-31830
    OEM 2021 Lexus ES350 Cap Sub-Assy, Radiator - 16401-31830
    Product Specifications
    • Notes: Es350; 3.5 Liter
    • Other Names: Radiator Cap
    • Item Weight: 0.40 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Cap Sub-Assy, Radiator
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $14.70 MSRP: $18.82
    You Save: $4.12 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Inlet Sub-Assembly, WATE

    PartNumber: 16031-31031
    OEM 2021 Lexus ES350 Inlet Sub-Assembly, WATE - 16031-31031
    Product Specifications
    • Notes: Es350; 3.5 Liter
    • Other Names: Thermostat, Water Inlet
    • Item Weight: 1.20 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16031-31030
    • Part Description: 2021 Lexus ES350 Inlet Sub-Assembly, WATE
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $44.13 MSRP: $56.57
    You Save: $12.44 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Inlet Sub-Assembly, WATE

    PartNumber: 16031-31031
    OEM 2021 Lexus ES350 Inlet Sub-Assembly, WATE - 16031-31031
    Product Specifications
    • Notes: Es350; 3.5 Liter
    • Other Names: Thermostat, Water Inlet
    • Item Weight: 1.20 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 16031-31030
    • Part Description: 2021 Lexus ES350 Inlet Sub-Assembly, WATE
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $44.13 MSRP: $56.57
    You Save: $12.44 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Radiator Assembly

    PartNumber: 16400-F0010
    OEM 2021 Lexus ES350 Radiator Assembly - 16400-F0010
    Product Specifications
    • Notes: Es350; Usa Built
    • Other Names: Radiator
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Radiator Assembly
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $262.76 MSRP: $355.92
    You Save: $93.16 (27%)
  • OEM (Genuine) 2021 Lexus ES350 Fan Assembly, W/MOTOR

    PartNumber: 16360-31500
    OEM 2021 Lexus ES350 Fan Assembly, W/MOTOR - 16360-31500
    Product Specifications
    • Notes: 3.5 Liter, Japan Built; Es350; Japan Built
    • Other Names: Fan Assembly, Fan Module
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Fan Assembly, W/MOTOR
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $1213.40 MSRP: $1670.82
    You Save: $457.42 (28%)
  • OEM (Genuine) 2021 Lexus ES350 Fan Assembly, W/MOTOR

    PartNumber: 16360-31500
    OEM 2021 Lexus ES350 Fan Assembly, W/MOTOR - 16360-31500
    Product Specifications
    • Notes: 3.5 Liter, Japan Built; Es350; Japan Built
    • Other Names: Fan Assembly, Fan Module
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Fan Assembly, W/MOTOR
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $1213.40 MSRP: $1670.82
    You Save: $457.42 (28%)
  • OEM (Genuine) 2021 Lexus ES350 Filler Sub-Assembly, Wat

    PartNumber: 16502-0P031
    OEM 2021 Lexus ES350 Filler Sub-Assembly, Wat - 16502-0P031
    Product Specifications
    • Notes: Es350; Usa Built; 3.5 Liter, US Built
    • Other Names: Filler Neck
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Filler Sub-Assembly, Wat
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $25.82 MSRP: $33.10
    You Save: $7.28 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Hose, Water By-Pass

    PartNumber: 16282-0P040
    OEM 2021 Lexus ES350 Hose, Water By-Pass - 16282-0P040
    Product Specifications
    • Notes: 3.5 Liter, Japan Built;3.5 Liter, US Built; 3.5 Liter, US Built
    • Other Names: Elbow, Hose Assembly
    • Fitment Type: Direct Replacement
    • Replaces: 16282-31100
    • Part Description: 2021 Lexus ES350 Hose, Water By-Pass
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $23.50 MSRP: $30.12
    You Save: $6.62 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Hose, Water By-Pass

    PartNumber: 16282-0P040
    OEM 2021 Lexus ES350 Hose, Water By-Pass - 16282-0P040
    Product Specifications
    • Notes: 3.5 Liter, Japan Built;3.5 Liter, US Built; 3.5 Liter, US Built
    • Other Names: Elbow, Hose Assembly
    • Fitment Type: Direct Replacement
    • Replaces: 16282-31100
    • Part Description: 2021 Lexus ES350 Hose, Water By-Pass
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $23.50 MSRP: $30.12
    You Save: $6.62 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Engine Water Pump Assembly

    PartNumber: 16100-09690
    OEM 2021 Lexus ES350 Engine Water Pump Assembly - 16100-09690
    Product Specifications
    • Notes: Es350; Usa Built; 3.5 Liter, US Built
    • Other Names: Water Pump
    • Item Weight: 3.10 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Engine Water Pump Assembly
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $130.68 MSRP: $173.75
    You Save: $43.07 (25%)
  • OEM (Genuine) 2021 Lexus ES350 Fan Assembly, W/MOTOR

    PartNumber: 16360-0P170
    OEM 2021 Lexus ES350 Fan Assembly, W/MOTOR - 16360-0P170
    Product Specifications
    • Notes: 3.5 Liter, US Built; Es350; Usa Built
    • Other Names: Fan Assembly, Fan Module
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Fan Assembly, W/MOTOR
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $1088.37 MSRP: $1498.66
    You Save: $410.29 (28%)
  • OEM (Genuine) 2021 Lexus ES350 Fan Assembly, W/MOTOR

    PartNumber: 16360-0P170
    OEM 2021 Lexus ES350 Fan Assembly, W/MOTOR - 16360-0P170
    Product Specifications
    • Notes: 3.5 Liter, US Built; Es350; Usa Built
    • Other Names: Fan Assembly, Fan Module
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Fan Assembly, W/MOTOR
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $1088.37 MSRP: $1498.66
    You Save: $410.29 (28%)
  • OEM (Genuine) 2021 Lexus ES350 Sensor, Water Temper

    PartNumber: 89422-47010
    OEM 2021 Lexus ES350 Sensor, Water Temper - 89422-47010
    Product Specifications
    • Notes: Es350
    • Other Names: Coolant Temperature Sensor, Temperature Sensor
    • Item Weight: 0.20 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Sensor, Water Temper
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $63.06 MSRP: $80.82
    You Save: $17.76 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Radiator Assembly Compatible

    PartNumber: 16400-F0021
    OEM 2021 Lexus ES350 Radiator Assembly Compatible - 16400-F0021
    Product Specifications
    • Other Names: Radiator, Radiator Assembly
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Radiator Assembly Compatible
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $378.55 MSRP: $512.76
    You Save: $134.21 (27%)
  • OEM (Genuine) 2021 Lexus ES350 Radiator Assembly

    PartNumber: 16400-25190
    OEM 2021 Lexus ES350 Radiator Assembly - 16400-25190
    Product Specifications
    • Notes: Es350; Japan Built; To 11/2020; 3.5 Liter, Japan Built
    • Other Names: Radiator
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Radiator Assembly
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $281.93 MSRP: $381.89
    You Save: $99.96 (27%)
  • OEM (Genuine) 2021 Lexus ES350 Radiator Assembly

    PartNumber: 16400-25130
    OEM 2021 Lexus ES350 Radiator Assembly - 16400-25130
    Product Specifications
    • Notes: Es350; Japan Built; From 11/2020
    • Other Names: Radiator
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Radiator Assembly
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $262.76 MSRP: $355.92
    You Save: $93.16 (27%)
  • OEM (Genuine) 2021 Lexus ES350 Water Pump Assembly

    PartNumber: 16100-39616
    OEM 2021 Lexus ES350 Water Pump Assembly - 16100-39616
    Product Specifications
    • Notes: Es350; Japan Built; 3.5 Liter, Japan Built
    • Other Names: Water Pump
    • Fitment Type: Direct Replacement
    • Replaces: 16100-39615
    • Part Description: 2021 Lexus ES350 Water Pump Assembly
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $126.40 MSRP: $166.38
    You Save: $39.98 (25%)
  • OEM (Genuine) 2021 Lexus ES350 Reserve Tank Assembly, R

    PartNumber: 16470-25042
    OEM 2021 Lexus ES350 Reserve Tank Assembly, R - 16470-25042
    Product Specifications
    • Notes: Es350; Japan Built; 3.5 Liter, Japan Built
    • Other Names: Expansion Tank, Reservoir
    • Fitment Type: Direct Replacement
    • Replaces: 16470-25041
    • Part Description: 2021 Lexus ES350 Reserve Tank Assembly, R
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $93.70 MSRP: $122.93
    You Save: $29.23 (24%)
  • OEM (Genuine) 2021 Lexus ES350 PULLEY, Water Pump

    PartNumber: 16173-0P011
    OEM 2021 Lexus ES350 PULLEY, Water Pump - 16173-0P011
    Product Specifications
    • Notes: Es350; 3.5 Liter, Japan Built;3.5 Liter, US Built
    • Other Names: Pulley
    • Fitment Type: Direct Replacement
    • Replaces: 16173-0P010, 16173-31031, 16173-31030
    • Part Description: 2021 Lexus ES350 PULLEY, Water Pump
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $95.32 MSRP: $125.04
    You Save: $29.72 (24%)
  • OEM (Genuine) 2021 Lexus ES350 Hose Assembly, Water By

    PartNumber: 16260-0P100
    OEM 2021 Lexus ES350 Hose Assembly, Water By - 16260-0P100
    Product Specifications
    • Notes: 3.5 Liter, US Built Only
    • Other Names: Hose Assembly
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Hose Assembly, Water By
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $91.05 MSRP: $119.45
    You Save: $28.40 (24%)
  • OEM (Genuine) 2021 Lexus ES350 Reserve Tank Assembly, R

    PartNumber: 16470-F0011
    OEM 2021 Lexus ES350 Reserve Tank Assembly, R - 16470-F0011
    Product Specifications
    • Notes: Es350; Usa Built; 3.5 Liter, US Built
    • Other Names: Expansion Tank, Reservoir
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Reserve Tank Assembly, R
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $84.34 MSRP: $110.64
    You Save: $26.30 (24%)
  • OEM (Genuine) 2021 Lexus ES350 Hose Assembly, Water By

    PartNumber: 16260-F0021
    OEM 2021 Lexus ES350 Hose Assembly, Water By - 16260-F0021
    Product Specifications
    • Other Names: Hose Assembly, Valve Assembly, Water Valve
    • Fitment Type: Direct Replacement
    • Replaces: 16260-25021
    • Part Description: 2021 Lexus ES350 Hose Assembly, Water By
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $73.99 MSRP: $97.07
    You Save: $23.08 (24%)
  • OEM (Genuine) 2021 Lexus ES350 Outlet, Water

    PartNumber: 16331-31230
    OEM 2021 Lexus ES350 Outlet, Water - 16331-31230
    Product Specifications
    • Notes: Es350; 3.5 Liter
    • Other Names: Water Outlet
    • Item Weight: 0.70 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Outlet, Water
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $50.05 MSRP: $64.16
    You Save: $14.11 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Outlet, Water

    PartNumber: 16331-31230
    OEM 2021 Lexus ES350 Outlet, Water - 16331-31230
    Product Specifications
    • Notes: Es350; 3.5 Liter
    • Other Names: Water Outlet
    • Item Weight: 0.70 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Outlet, Water
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $50.05 MSRP: $64.16
    You Save: $14.11 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Outlet, Water

    PartNumber: 16331-31230
    OEM 2021 Lexus ES350 Outlet, Water - 16331-31230
    Product Specifications
    • Notes: Es350; 3.5 Liter
    • Other Names: Water Outlet
    • Item Weight: 0.70 Pounds
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Outlet, Water
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $50.05 MSRP: $64.16
    You Save: $14.11 (22%)
  • OEM (Genuine) 2021 Lexus ES350 THERMISTOR Assembly, Air

    PartNumber: 88620-0E050
    OEM 2021 Lexus ES350 THERMISTOR Assembly, Air - 88620-0E050
    Product Specifications
    • Notes: Es350, Es250; Es350
    • Item Weight: 0.20 Pounds
    • Fitment Type: Direct Replacement
    • Replaces: 88620-28050
    • Part Description: 2021 Lexus ES350 THERMISTOR Assembly, Air
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $40.66 MSRP: $52.12
    You Save: $11.46 (22%)
  • OEM (Genuine) 2021 Lexus ES350 Hose, Radiator, NO.3

    PartNumber: 16573-31080
    OEM 2021 Lexus ES350 Hose, Radiator, NO.3 - 16573-31080
    Product Specifications
    • Notes: Es350; Japan Built; 3.5 Liter, Japan Built
    • Location: Driver Side
    • Other Names: Lower Hose, Radiator Hose
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Hose, Radiator, NO.3
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $32.58 MSRP: $41.77
    You Save: $9.19 (23%)
  • OEM (Genuine) 2021 Lexus ES350 Hose, Radiator, NO.3

    PartNumber: 16573-31080
    OEM 2021 Lexus ES350 Hose, Radiator, NO.3 - 16573-31080
    Product Specifications
    • Notes: Es350; Japan Built; 3.5 Liter, Japan Built
    • Location: Driver Side
    • Other Names: Lower Hose, Radiator Hose
    • Fitment Type: Direct Replacement
    • Part Description: 2021 Lexus ES350 Hose, Radiator, NO.3
    More Info
    Vehicle Fitment
    • 2021 Lexus ES350 | Base, F Sport, Luxury, Ultra Luxury | 6 Cyl 3.5 L GAS
    $32.58 MSRP: $41.77
    You Save: $9.19 (23%)
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